Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5164515

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at AhR in mouse Hepa2Dluc cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type Hepa2Dluc
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Aryl hydrocarbon receptor (CHEMBL6099)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
Grycová A, Joo H, Maier V, Illés P, Vyhlídalová B, Poulíková K, Sládeková L, Nádvorník P, Vrzal R, Zemánková L, Pečinková P, Poruba M, Zapletalová I, Večeřa R, Anzenbacher P, Ehrmann J, Ondra P, Jung JW, Mani S, Dvořák Z.
J Med Chem (2022) 65 : 6859 -6868
PubMed 35416668 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1324296 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1324296 EC50 = 10.0 nM 8.00