Assay Detail
Binding
CHEMBL5165920
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant JAK3 expressed in baculovirus sf9 insect cells using GGEEEEYFELVKKKK as substrate measured after 30 mins in presence of ATP by ADP-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.92 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5178368 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5178368 | — | IC50 | = | 119.0 | nM | 6.92 |