Assay Detail
Binding
CHEMBL5166836
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to MAGEA4 (unknown origin) expressed in Escherichia coli BL21-(DE3) by isothermal titration calorimetry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.54 | 7.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5187815 | — | — | 1 | 7.93 |
| CHEMBL5188210 | — | — | 1 | 7.43 |
| CHEMBL5199001 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5187815 | — | Kd | = | 11.8 | nM | 7.93 |
| CHEMBL5188210 | — | Kd | = | 36.8 | nM | 7.43 |
| CHEMBL5199001 | — | Kd | = | 55.5 | nM | 7.26 |