Assay Detail
Functional
CHEMBL5167650
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Antiproliferative activity against human SU-DHL-6 cells assessed as cell growth inhibition incubated for 96 hrs by cell titer glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SU-DHL-6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and Optimization of Thienopyrimidine Derivatives as Potent and Selective PI3Kδ Inhibitors for the Treatment of B-Cell Malignancies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.98 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3643413 | LENIOLISIB | 4.0 | 1 | 6.11 |
| CHEMBL5204818 | — | — | 1 | 5.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3643413 | LENIOLISIB | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL5204818 | — | IC50 | = | 1430.0 | nM | 5.84 |