Assay Detail

CHEMBL5214409

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Binding

Selectivity interaction (CEREP ligand profiling ) EUB0000351a LTB4R

ChEMBL ↗

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Target

Leukotriene B4 receptor 1 (CHEMBL3911) ↗

Open DB target context

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Leukotriene B4 receptor 1 (CHEMBL3911) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Leukotriene B4 receptor 1

CHEMBL3911

Anchored from Assay target.

Protein identity Leukotriene B4 receptor 1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Leukotriene B4 receptor 1 (CHEMBL3911) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomics Library wave 3

EUbOPEN
(2023)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.01	5.01

Assay Parameters

Parameter	Type	Value	Units	Text
Protein family	Protein family	-	—	GPCR

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3286797	PF-04418948	1.0	1	5.01

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3286797	PF-04418948	IC50	=	9700.0	nM	5.01