Assay Detail

CHEMBL5214575

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Binding

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000549a TMEM97

ChEMBL ↗

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Target

Sigma intracellular receptor 2 (CHEMBL4105907) ↗

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Primary target Sigma intracellular receptor 2

CHEMBL4105907

Anchored from Assay target.

Protein identity Sigma intracellular receptor 2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Sigma intracellular receptor 2 (CHEMBL4105907) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomics Library wave 3

EUbOPEN
(2023)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	6.25	6.25

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4577237	BI 9446	—	1	6.25

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4577237	BI 9446	Ki	=	557.65	nM	6.25