Assay Detail
Binding
CHEMBL5214634
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Selectivity interaction (Methyltransferase panel (HotSpot screen, Reaction Biology, radioisotope-based filter binding assays)) EUB0000215b EZH1
1
Total Activities
1
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | Selectivity assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase EZH1 (CHEMBL2189116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.62 | 6.62 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Protein family | Protein family | - | — | HMT |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2204995 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2204995 | — | IC50 | = | 240.0 | nM | 6.62 |