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Assay Detail

CHEMBL5215386

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human Hep3B cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Hep 3B2
Confidence 1 — Organism
Curated By Autocuration

Target

Hep 3B2 (CHEMBL4296437)
Type CELL-LINE
Organism Homo sapiens

Publication

Antitumor potential of the protein phosphatase inhibitor, cantharidin, and selected derivatives.
Ren Y, Kinghorn AD.
Bioorg Med Chem (2021) 32 : 116012 -116012
PubMed 33454654 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5220940 1 6.40
CHEMBL5218531 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5220940 IC50 = 400.0 nM 6.40
CHEMBL5218531 IC50 > 2000000.0 nM -