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Assay Detail

CHEMBL5216169

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse MC3T3-E1 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type MC3T3-E1
Confidence 1 — Organism
Curated By Autocuration

Target

MC3T3-E1 (CHEMBL4296463)
Type CELL-LINE
Organism Mus musculus

Publication

Melphalan: Recent insights on synthetic, analytical and medicinal aspects.
Pahwa R, Chhabra J, Kumar R, Narang R.
Eur J Med Chem (2022) 238 : 114494 -114494
PubMed 35665692 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.14 6.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL852 MELPHALAN 4.0 1 6.17
CHEMBL5219154 1 6.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL852 MELPHALAN IC50 = 680.0 nM 6.17
CHEMBL5219154 IC50 = 790.0 nM 6.10