Assay Detail
Functional
CHEMBL5216354
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against Staphylococcus aureus NCIM 2010 assessed as reduction in bacterial growth incubated for 8 hrs by absorbance based assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.70 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1082 | AMOXICILLIN | 4.0 | 1 | 6.82 |
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 6.82 |
| CHEMBL5220992 | — | — | 1 | 6.82 |
| CHEMBL5218479 | — | — | 1 | 6.82 |
| CHEMBL5219187 | — | — | 1 | 6.80 |
| CHEMBL5219555 | — | — | 1 | 6.80 |
| CHEMBL5219360 | — | — | 1 | 6.75 |
| CHEMBL5220084 | — | — | 1 | 6.58 |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | 4.0 | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1082 | AMOXICILLIN | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL174 | AMPICILLIN | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5220992 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5218479 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5219187 | — | EC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5219555 | — | EC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5219360 | — | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL5220084 | — | EC50 | = | 260.0 | nM | 6.58 |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | EC50 | = | 770.0 | nM | 6.11 |