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Assay Detail

CHEMBL5216367

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human plasma BChE using S-butyrylthiocholine as substrate by Ellman's method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL1914)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Zhang H, Wang Y, Wang Y, Li X, Wang S, Wang Z.
Eur J Med Chem (2022) 240 : 114606 -114606
PubMed 35858523 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.17 8.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL205231 1 8.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL205231 IC50 = 6.7 nM 8.17