Assay Detail
Binding
CHEMBL5216391
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Inhibition of rat AChE
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.32 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL197696 | — | — | 1 | 7.85 |
| CHEMBL194372 | — | — | 1 | 7.00 |
| CHEMBL5220738 | — | — | 1 | 5.92 |
| CHEMBL521589 | BAMBUTEROL | 3.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL197696 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL194372 | — | IC50 | = | 101.0 | nM | 7.00 |
| CHEMBL5220738 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL521589 | BAMBUTEROL | IC50 | = | 30000.0 | nM | 4.52 |