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Assay Detail

CHEMBL5216431

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat BChE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Butyrylcholinesterase (CHEMBL3403)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Zhang H, Wang Y, Wang Y, Li X, Wang S, Wang Z.
Eur J Med Chem (2022) 240 : 114606 -114606
PubMed 35858523 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL521589 BAMBUTEROL 3.0 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL521589 BAMBUTEROL IC50 = 3.0 nM 8.52