Assay Detail
Binding
CHEMBL5216549
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Inhibition of IDO1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.02 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4536439 | — | — | 1 | 6.30 |
| CHEMBL4595323 | — | — | 1 | 4.75 |
| CHEMBL4465170 | — | — | 1 | 4.00 |
| CHEMBL1475252 | TENATOPRAZOLE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4536439 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4595323 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL4465170 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL1475252 | TENATOPRAZOLE | IC50 | > | 100000.0 | nM | - |