Compound Detail
CHEMBL1475252
TENATOPRAZOLE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1475252 |
| Name | TENATOPRAZOLE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | ZBFDAUIVDSSISP-UHFFFAOYSA-N |
| Active Moiety | CHEMBL4802234 |
8
Targets
13
Activities
1
Assay Types
0
PK Parameters
20
Publications
4
Known Names
1
Indications
Molecular Properties
346.4
MW (Da)
2.29
ALogP
6
HBA
1
HBD
96.0
PSA (Ų)
0.71
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Indications
Esophagitis, Peptic
Activity Summary
IC50 13 meas. best 7.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Giardia intestinalis CHEMBL612652 | IC50 | 7.72 | 7.506 | 19.0 | 5 |
| Plasmodium berghei CHEMBL612653 | IC50 | 6.65 | 6.65 | 224.0 | 1 |
| Replicase polyprotein 1ab CHEMBL4523582 | IC50 | 6.01 | 6.01 | 970.0 | 1 |
| Indoleamine 2,3-dioxygenase 2 CHEMBL2189159 | IC50 | 5.75 | 5.75 | 1800.0 | 1 |
| Indoleamine 2,3-dioxygenase 2 CHEMBL3627587 | IC50 | 5.75 | 5.75 | 1800.0 | 1 |
| NAD(+) hydrolase SARM1 CHEMBL4523350 | IC50 | 5.13 | 5.095 | 7400.0 | 2 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 CHEMBL6036 | IC50 | 5.11 | 5.11 | 7800.0 | 1 |
| Cytosolic endo-beta-N-acetylglucosaminidase CHEMBL5172 | IC50 | 4.7 | 4.7 | 20000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine