Indoleamine 2,3-dioxygenase 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8R0V5. Use UniProt Q8R0V5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8R0V5 as the stable identity anchor, then attach disease evidence before program review.
Indoleamine 2,3-dioxygenase 2
Review this target as Indoleamine 2,3-dioxygenase 2, mapped to UniProt Q8R0V5. Sequence length is 405 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Indoleamine 2,3-dioxygenase 2 as ChEMBL target CHEMBL2189159, mapped to UniProt Q8R0V5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Indoleamine 2,3-dioxygenase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8R0V5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Indoleamine 2,3-dioxygenase 2 |
| UniProt Accession | Q8R0V5 |
| Component Type | Protein |
| Sequence Length | 405 aa |
Indoleamine 2,3-dioxygenase 2
Review this target as Indoleamine 2,3-dioxygenase 2, mapped to UniProt Q8R0V5. Sequence length is 405 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL193 | 5.82 | IC50 | 1500.0 | Approved |
| CHEMBL1475252 | 5.75 | IC50 | 1800.0 | Clinical |
| CHEMBL192 | 5.35 | IC50 | 4500.0 | Approved |
| CHEMBL408 | 5.35 | IC50 | 4500.0 | Approved |
| CHEMBL104 | 5.23 | IC50 | 5900.0 | Approved |
| CHEMBL91 | 5.17 | IC50 | 6700.0 | Approved |
| CHEMBL4578334 | 5.12 | IC50 | 7680.0 | Preclinical |
| CHEMBL808 | 5.12 | IC50 | 7600.0 | Approved |
| CHEMBL480 | 5.09 | IC50 | 8200.0 | Approved |
| CHEMBL4438707 | 5.06 | IC50 | 8770.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 44 | 4.9 |