Assay Detail
Functional
CHEMBL5216575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HL-60 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.37 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL193589 | — | — | 1 | 7.52 |
| CHEMBL36501 | — | — | 1 | 7.22 |
| CHEMBL5219125 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL193589 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL36501 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL5219125 | — | IC50 | < | 12.5 | nM | - |