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Assay Detail

CHEMBL5216586

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against HEK293 cells assessed as cell growth inhibition incubated for 96 hrs by WST-8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEK293
Confidence 1 — Organism
Curated By Autocuration

Target

HEK293 (CHEMBL614818)
Type CELL-LINE
Organism Homo sapiens

Publication

A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Shahari MSB, Dolzhenko AV.
Eur J Med Chem (2022) 241 : 114645 -114645
PubMed 35981459 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.45 7.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5219496 1 7.60
CHEMBL5219455 1 7.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5219496 IC50 = 25.0 nM 7.60
CHEMBL5219455 IC50 = 51.0 nM 7.29