Assay Detail
Functional
CHEMBL5216623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against NNRTI resistant HIV1 harboring Lys103Asn mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.71 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304055 | — | — | 1 | 8.52 |
| CHEMBL307297 | — | — | 1 | 7.40 |
| CHEMBL313405 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304055 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL307297 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL313405 | — | IC50 | = | 63.0 | nM | 7.20 |