Assay Detail
Binding
CHEMBL5217010
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant AChE using S-acetylthiocholine as substrate by DTNB reagent based spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Isatoic anhydrides as novel inhibitors of monoamine oxidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.77 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 5.93 |
| CHEMBL5219958 | — | — | 1 | 4.26 |
| CHEMBL5219594 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | IC50 | = | 1180.0 | nM | 5.93 |
| CHEMBL5219958 | — | IC50 | = | 55000.0 | nM | 4.26 |
| CHEMBL5219594 | — | IC50 | = | 76200.0 | nM | 4.12 |