Assay Detail
Binding
CHEMBL5217154
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Inhibition of PEST(unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 12 (CHEMBL3236) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.14 | 4.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4794972 | — | — | 1 | 4.14 |
| CHEMBL5219519 | — | — | 1 | - |
| CHEMBL5218807 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4794972 | — | IC50 | = | 72000.0 | nM | 4.14 |
| CHEMBL5219519 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5218807 | — | IC50 | > | 10000.0 | nM | - |