Assay Detail
Binding
CHEMBL5223558
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Inhibition of AChE (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances on synthesis and biological activities of aurones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.50 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5285953 | — | — | 1 | 7.35 |
| CHEMBL3416669 | — | — | 1 | 6.80 |
| CHEMBL5267000 | — | — | 1 | 6.46 |
| CHEMBL3416658 | — | — | 1 | 6.38 |
| CHEMBL5272095 | — | — | 1 | 6.26 |
| CHEMBL3416657 | — | — | 1 | 6.19 |
| CHEMBL3416654 | — | — | 1 | 6.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5285953 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL3416669 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5267000 | — | IC50 | = | 348.0 | nM | 6.46 |
| CHEMBL3416658 | — | IC50 | = | 422.0 | nM | 6.38 |
| CHEMBL5272095 | — | IC50 | = | 545.0 | nM | 6.26 |
| CHEMBL3416657 | — | IC50 | = | 643.0 | nM | 6.19 |
| CHEMBL3416654 | — | IC50 | = | 845.0 | nM | 6.07 |