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Assay Detail

CHEMBL5223606

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Functional
Antiproliferative activity against BCL-6 dependent human SU-DHL-4 cells by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SUD4
Confidence 1 — Organism
Curated By Autocuration

Target

SUD4 (CHEMBL613711)
Type CELL-LINE
Organism Homo sapiens

Publication

Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.
Ai Y, Hwang L, MacKerell AD, Melnick A, Xue F.
J Med Chem (2021) 64 : 4333 -4358
PubMed 33844535 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4538610 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4538610 IC50 = 1000.0 nM 6.00