Assay Detail
Binding
CHEMBL5223638
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Binding affinity to human 5'-biotin-double stranded DNA assessed as dissociation equilibrium constant by surface plasmon resonance
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.69 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5276924 | — | — | 1 | 8.08 |
| CHEMBL5268128 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5276924 | — | Kd | = | 8.28 | nM | 8.08 |
| CHEMBL5268128 | — | Kd | = | 49.9 | nM | 7.30 |