Assay Detail
Binding
CHEMBL5223689
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human A2a adenosine receptor
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Caffeine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.02 | 5.02 |
| Ki | 1 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL113 | CAFFEINE | 4.0 | 2 | 5.02 |
| CHEMBL1114 | THEOBROMINE | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL113 | CAFFEINE | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL113 | CAFFEINE | Ki | = | 50118.72 | nM | 4.30 |
| CHEMBL1114 | THEOBROMINE | IC50 | > | 250000.0 | nM | - |