Assay Detail
Binding
CHEMBL5223693
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Binding affinity to human A1 adenosine receptor assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Caffeine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.47 | 9.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298474 | — | — | 1 | 9.02 |
| CHEMBL11002 | — | — | 1 | 8.19 |
| CHEMBL158077 | — | — | 1 | 8.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298474 | — | Ki | = | 0.95 | nM | 9.02 |
| CHEMBL11002 | — | Ki | = | 6.5 | nM | 8.19 |
| CHEMBL158077 | — | Ki | = | 6.5 | nM | 8.19 |