Assay Detail
Toxicity
CHEMBL5224075
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Cytotoxicity against human THLE-2 cells assessed as cell growth inhibition
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | THLE-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Annual review of lysine-specific demethylase 1 (LSD1/KDM1A) inhibitors in 2021.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.24 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5290883 | — | — | 1 | 5.38 |
| CHEMBL4854446 | — | — | 1 | 5.32 |
| CHEMBL4863608 | — | — | 1 | 5.15 |
| CHEMBL3759201 | — | — | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5290883 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL4854446 | — | IC50 | = | 4760.0 | nM | 5.32 |
| CHEMBL4863608 | — | IC50 | = | 7070.0 | nM | 5.15 |
| CHEMBL3759201 | — | IC50 | = | 7830.0 | nM | 5.11 |