Assay Detail
Binding
CHEMBL5224202
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Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured after 5 mins by DTNB reagent based Ellman's method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advancements in chromone as a privileged scaffold towards the development of small molecules for neurodegenerative therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.15 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270046 | — | — | 1 | 5.30 |
| CHEMBL5270908 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270046 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL5270908 | — | IC50 | = | 10000.0 | nM | 5.00 |