Assay Detail
Functional
CHEMBL5224299
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Antiproliferative activity against human MV4-11 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Homobivalent, Trivalent, and Covalent PROTACs: Emerging Strategies for Protein Degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.98 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5279987 | — | — | 1 | 8.96 |
| CHEMBL4226570 | — | — | 1 | 7.95 |
| CHEMBL5289872 | — | — | 1 | 7.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5279987 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL4226570 | — | IC50 | = | 11.3 | nM | 7.95 |
| CHEMBL5289872 | — | IC50 | = | 94.6 | nM | 7.02 |