Assay Detail
Functional
CHEMBL5224308
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Antiproliferative activity against human SU-DHL-1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SU-DHL-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Homobivalent, Trivalent, and Covalent PROTACs: Emerging Strategies for Protein Degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.94 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4161454 | — | — | 1 | 7.80 |
| CHEMBL5276252 | — | — | 1 | 6.70 |
| CHEMBL5278796 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4161454 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL5276252 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL5278796 | — | IC50 | = | 465.0 | nM | 6.33 |