Assay Detail
Binding
CHEMBL5224426
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK1/Cyclin B (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cyclin-dependent kinase 1/cyclin B (CHEMBL2094127) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
CDK9 inhibitors in cancer research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.51 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287128 | — | — | 1 | 8.15 |
| CHEMBL5202522 | — | — | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287128 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5202522 | — | IC50 | = | 138.0 | nM | 6.86 |