Assay Detail
Binding
CHEMBL5225333
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Inhibition of HDAC4 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington's Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.09 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5286810 | — | — | 1 | 7.40 |
| CHEMBL5269131 | — | — | 1 | 7.27 |
| CHEMBL3793392 | — | — | 1 | 7.00 |
| CHEMBL3110021 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5286810 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL5269131 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL3793392 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3110021 | — | IC50 | = | 200.0 | nM | 6.70 |