Assay Detail
Binding
CHEMBL5225737
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Antagonist activity at GPR55 (unknown origin) by beta-arrestin recruitment assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.14 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1567371 | — | — | 1 | 6.30 |
| CHEMBL1402920 | — | — | 1 | 6.16 |
| CHEMBL5275934 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1567371 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL1402920 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL5275934 | — | IC50 | = | 1100.0 | nM | 5.96 |