Assay Detail
Binding
CHEMBL5226623
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Inhibition of PDE1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.03 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4095097 | — | — | 1 | 8.52 |
| CHEMBL4067682 | — | — | 1 | 7.58 |
| CHEMBL71752 | VINPOCETINE | 2.0 | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4095097 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4067682 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL71752 | VINPOCETINE | IC50 | = | 10000.0 | nM | 5.00 |