Assay Detail
Binding
CHEMBL5226845
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EBP (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (CHEMBL4931) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.36 | 8.53 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5285995 | — | — | 1 | 8.53 |
| CHEMBL4454956 | — | — | 1 | 8.03 |
| CHEMBL5281526 | — | — | 1 | 7.31 |
| CHEMBL4544901 | — | — | 1 | 7.01 |
| CHEMBL5270628 | — | — | 1 | 6.73 |
| CHEMBL5285729 | — | — | 1 | 6.52 |
| CHEMBL5284923 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5285995 | — | IC50 | = | 2.95 | nM | 8.53 |
| CHEMBL4454956 | — | IC50 | = | 9.36 | nM | 8.03 |
| CHEMBL5281526 | — | IC50 | = | 49.0 | nM | 7.31 |
| CHEMBL4544901 | — | IC50 | = | 97.3 | nM | 7.01 |
| CHEMBL5270628 | — | IC50 | = | 188.0 | nM | 6.73 |
| CHEMBL5285729 | — | IC50 | = | 303.0 | nM | 6.52 |
| CHEMBL5284923 | — | IC50 | < | 1000.0 | nM | - |