Assay Detail
Functional
CHEMBL5226900
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Antiproliferative activity against human DLD-1 cells assessed as reduction in cell proliferation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DLD-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.51 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL556 | DEFEROXAMINE | 4.0 | 1 | 5.54 |
| CHEMBL550348 | DEFERASIROX | 4.0 | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL556 | DEFEROXAMINE | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL550348 | DEFERASIROX | IC50 | = | 3400.0 | nM | 5.47 |