Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5227038

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human Cathepsin L using Z-Phe-Arg-AMC as substrate incubated for 4 hrs by fluorometric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Procathepsin L (CHEMBL3837)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The race to treat COVID-19: Potential therapeutic agents for the prevention and treatment of SARS-CoV-2.
Shagufta, Ahmad I.
Eur J Med Chem (2021) 213 : 113157 -113157
PubMed 33486200 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.60 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL423112 1 8.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL423112 IC50 = 2.5 nM 8.60