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Assay Detail

CHEMBL5227047

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against wild type MERS-CoV infected in HEK293T/17 cells assessed as inhibition of viral replication by immunoblotting assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Middle East respiratory syndrome-related coronavirus
Confidence 1 — Organism
Curated By Autocuration

Target

Middle East respiratory syndrome-related coronavirus (CHEMBL4296578)
Type ORGANISM
Organism Middle East respiratory syndrome-related coronavirus

Publication

The race to treat COVID-19: Potential therapeutic agents for the prevention and treatment of SARS-CoV-2.
Shagufta, Ahmad I.
Eur J Med Chem (2021) 213 : 113157 -113157
PubMed 33486200 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.12 4.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3126388 1 4.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3126388 IC50 = 75000.0 nM 4.12