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Assay Detail

CHEMBL5227413

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at human GPR120 expressed in CHO-K1 cells assessed as calcium accumulation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO-K1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Free fatty acid receptor 4 (CHEMBL5339)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery.
Carullo G, Mazzotta S, Vega-Holm M, Iglesias-Guerra F, Vega-Pérez JM, Aiello F, Brizzi A.
J Med Chem (2021) 64 : 4312 -4332
PubMed 33843223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.92 6.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5286838 1 6.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5286838 EC50 = 120.0 nM 6.92