Assay Detail
Binding
CHEMBL5227556
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Inhibition of PDE1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Advances in Cyclic Nucleotide Phosphodiesterase-Targeted PET Imaging and Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.39 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270640 | — | — | 1 | 7.89 |
| CHEMBL5272911 | — | — | 1 | 6.77 |
| CHEMBL71752 | VINPOCETINE | 2.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270640 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL5272911 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL71752 | VINPOCETINE | IC50 | = | 30000.0 | nM | 4.52 |