Assay Detail
Functional
CHEMBL5227772
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Antiproliferative activity against human EA.hy 926 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | EA.hy 926 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.86 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 7.96 |
| CHEMBL5270399 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL5270399 | — | IC50 | = | 18.0 | nM | 7.75 |