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Assay Detail

CHEMBL5227784

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of tubulin depolymerization (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Tubulin (CHEMBL2095182)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.
Shuai W, Wang G, Zhang Y, Bu F, Zhang S, Miller DD, Li W, Ouyang L, Wang Y.
J Med Chem (2021) 64 : 7963 -7990
PubMed 34101463 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.23 5.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5279559 1 5.23

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5279559 IC50 = 5900.0 nM 5.23