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Assay Detail

CHEMBL5227816

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at human TLR7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Toll-like receptor 7 (CHEMBL5936)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structural Evolution and Translational Potential for Agonists and Antagonists of Endosomal Toll-like Receptors.
Talukdar A, Ganguly D, Roy S, Das N, Sarkar D.
J Med Chem (2021) 64 : 8010 -8041
PubMed 34107682 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1282 IMIQUIMOD 4.0 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1282 IMIQUIMOD EC50 = 2210.0 nM 5.66