Assay Detail
Binding
CHEMBL5227976
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human SIRT6 using labeled peptide Acp53 (Ac-Arg-His-Lys-Lys (Ac)-AMC) substrate by fluorometric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
NAD-dependent protein deacylase sirtuin-6 (CHEMBL2163182) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Emerging Therapeutic Potential of SIRT6 Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.48 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222382 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222382 | — | IC50 | = | 33200.0 | nM | 4.48 |