Assay Detail
Binding
CHEMBL5228800
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Inhibition of human recombinant MAGL by fluorometric analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.04 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3658400 | — | — | 1 | 8.38 |
| CHEMBL5274306 | — | — | 1 | 8.34 |
| CHEMBL5290125 | — | — | 1 | 7.75 |
| CHEMBL4640364 | — | — | 1 | 7.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3658400 | — | IC50 | = | 4.2 | nM | 8.38 |
| CHEMBL5274306 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL5290125 | — | IC50 | = | 17.8 | nM | 7.75 |
| CHEMBL4640364 | — | IC50 | = | 20.3 | nM | 7.69 |