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Assay Detail

CHEMBL5229157

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Binding
Inhibition of human ALKBH2 by HPLC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA oxidative demethylase ALKBH2 (CHEMBL5169164)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.
Perry GS, Das M, Woon ECY.
J Med Chem (2021) 64 : 16974 -17003
PubMed 34792334 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.04 5.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL418068 RHEIN 1 5.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL418068 RHEIN IC50 = 9100.0 nM 5.04