Assay Detail
Binding
CHEMBL5229172
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FTO (unknown origin)-mediated demethylation activity using 15-mer ssRNA with CUUGUCA(m6A)CAGCAGA sequence as substrate by reverse phase high-performance liquid chromatography
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Alpha-ketoglutarate-dependent dioxygenase FTO (CHEMBL2331065) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.56 | 4.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL235934 | CLAUSINE E | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL235934 | CLAUSINE E | IC50 | = | 27790.0 | nM | 4.56 |