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Assay Detail

CHEMBL5229178

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CCRF-CEM
Confidence 1 — Organism
Curated By Autocuration

Target

CCRF-CEM (CHEMBL382)
Type CELL-LINE
Organism Homo sapiens

Publication

Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.
Perry GS, Das M, Woon ECY.
J Med Chem (2021) 64 : 16974 -17003
PubMed 34792334 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.86 5.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4752151 1 5.86
CHEMBL4753950 1 5.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4752151 IC50 = 1380.0 nM 5.86
CHEMBL4753950 IC50 = 1380.0 nM 5.86