Assay Detail
Binding
CHEMBL5229225
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length LRH1 transfected in HEK293T cells incubated for 20 hrs by luciferase reporter assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nuclear receptor subfamily 5 group A member 2 (CHEMBL3544) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The Medicinal Chemistry and Therapeutic Potential of LRH-1 Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.97 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4303467 | — | — | 1 | 6.50 |
| CHEMBL1325149 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4303467 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL1325149 | — | IC50 | = | 3700.0 | nM | 5.43 |