Compound Detail
CHEMBL1325149
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Basic Information
| ChEMBL ID | CHEMBL1325149 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHMQQIFPOIZPIJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
388.9
MW (Da)
3.02
ALogP
5
HBA
1
HBD
61.3
PSA (Ų)
0.88
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nuclear receptor subfamily 5 group A member 2 CHEMBL3544 | IC50 | 5.43 | 5.43 | 3700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nuclear receptor subfamily 5 group A member 2 | IC50 | = | 3700.0 | nM | 5.43 | Inhibition of full length LRH1 transfected in HEK293T cells incubated for 20 hrs... | 34839661 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34839661 | 10.1021/acs.jmedchem.1c01663 | Nuclear receptor subfamily 5 group A member 2 | 2 |
| 32184971 | 10.1021/acsmedchemlett.9b00442 | Nuclear receptor subfamily 5 group A member 2 | 1 |
| 32184971 | 10.1021/acsmedchemlett.9b00442 | Steroidogenic factor 1 | 1 |
Data from ChEMBL 36 via Core Engine